Researchers warn of severe long-term damage to the brain after Covid following new study
“Researchers warn of severe long-term damage to the brain after Covid following new study.”
Understanding the long-term neurological effects of SARS-CoV-2 infection
Longitudinal evaluation of neurocognitive outcomes in a cohort with persistent post-COVID olfactory dysfunction
Is self-report brain fog after mild COVID-19 truly induced by COVID-19 infection? A longitudinal fNIRS study
Scientists Finally Know Why Some People Still Can’t Taste Anything Years After Having COVID
COVID-19 Uniquely Rewires the Brain Compared to the Flu
Intranasal SARS-CoV-2 infection changes the transcriptome of the mouse trigeminal ganglion and brainstem: potential mechanisms underlying headache and trigeminal pain presentation in COVID-19 - Journal of Neuroinflammation
A recent study suggests that SARS-CoV-2 may affect the trigeminal nerve and brainstem, which are involved in facial sensation and pain.
COVID-19 infection may alter brain microstructure even in people who fully recover
MRI Scans Reveal Your COVID-19 Can Leave Behind Nasty Brain Damage, Even After You “Recover”
What causes all the symptoms of long COVID and ME/CFS? The brainstem could be the key
COVID-19 associated neurological and psychological manifestations
Brain MR spectroscopy in long COVID
Changes in glutamate/glutamine balance, total N-acetyl-compound levels, and myo-inositol provided evidence of neuronal injury or loss, as well as of persistent neuroinflammation and glial dysfunction in the brains of patients with long COVID.
Frontiers | Viral reprogramming of glial metabolism as a driver of neuroinflammation
A new review highlights how neurotropic viruses like SARS-CoV-2 reprogram the metabolism of brain immune cells — especially microglia and astrocytes — contributing to neuroinflammation and brain dysfunction.
Altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals: A multimodal MRI study
COVID can leave silent but permanent effect on brain health. Researchers from Griffith University have found that COVID-19 can cause significant long-term brain alterations in those who had been infected, according to MRI brain scans.
COVID-19 leaves a lasting mark on the human brain
Comprehensive mapping of the signaling events evoked by SARS-CoV-2 variants delta and omicron in human astrocytes
Thread by @ZdenekVrozina on Thread Reader App
“A new study strengthens the view that SARS-CoV-2: disrupts brain homeostasis, alters ionic & neurotransmitter balance, and triggers lasting epigenetic reprogramming. Researchers exposed human primary astrocytes to Delta and Omicron. The results are striking🧵”
A new study strengthens the view that SARS-CoV-2:
disrupts brain homeostasis,
alters ionic & neurotransmitter balance,
and triggers lasting epigenetic reprogramming.
Researchers exposed human primary astrocytes to Delta and Omicron.
The results are striking🧵
Alterations of the amygdala in post-COVID olfactory dysfunction
University Hospital Schleswig-Holstein, 61 adults about 8 months after COVID were scanned by MRI.
Those with persistent smell loss showed structural changes in the amygdala linked to smell and emotion, along with higher anxiety and depression scores.
Mechanisms of sex differences in acute and long COVID sequelae in mice
Johns Hopkins scientists found that female mice recovering from COVID showed lasting memory loss and brain inflammation.
The effect was driven by having two X chromosomes, revealing a genetic cause for why long COVID hits women harder.
COVID-19 Linked to Lasting and Underrecognized Smell Impairment
Among adults with COVlD-related changes in smell and taste, 23% experience severe or total loss.
Importantly, the cumulative burden will increase with repeat infections, it diminishes quality of life, & it indicates neurological damage.
Brainstem damage found to be behind long-lasting effects of severe Covid-19
"Using ultra-high-resolution scanners that can see the living brain in fine detail, researchers from the Universities of Cambridge and Oxford were able to observe the damaging effects Covid-19 can have on the brain."
Thread by @JamesThrot on Thread Reader App
“SARS-CoV-2 isn’t just a respiratory virus. Emerging evidence shows it can infect human motor neurons. Could this link to motor neuron disease (MND)?”
COVID-19 infection associated with increased risk of new-onset vascular dementia in older adults
COVID-19 infection linked to a 41% higher risk of developing new-onset vascular dementia in older adults, with researchers warning that the virus may have lasting effects on brain and vascular health even after recovery.
Scientists reveal the one Covid symptom you may be stuck with for life
“It is well known that Covid can impair your sense of smell, but a new study has found that those who lose it may never get it back.”
It is well known that Covid can impair your sense of smell, but a new study has found that those who lose it may never get it back.
COVID-19 infection associated with increased risk of new-onset vascular dementia in adults ≥50 years
UK Biobank study of 54,757 adults aged 50+ found that COVID-19 survivors had a 41% higher risk of dementia and a 77% higher risk of vascular dementia after two years, especially in those unvaccinated or with mental illness.
Thread by @IntegralAnswers on Thread Reader App
“Thread: A molecular clue to Long COVID “brain fog”
1/ New study from Yokohama City Univ used PET imaging of AMPA receptors. Long COVID patients showed elevated AMPAR levels, linked to both cognitive impairment and inflammation. A molecular biomarker emerges.”
Thread: A molecular clue to Long COVID “brain fog”
1/ New study from Yokohama City Univ used PET imaging of AMPA receptors. Long COVID patients showed elevated AMPAR levels, linked to both cognitive impairment and inflammation. A molecular biomarker emerges.
Thread by @ZdenekVrozina on Thread Reader App
“COVID and brain fog. For millions, it’s the most disabling legacy of the pandemic. Now, a new brain imaging study reveals a clear biological basis - and the parallels with other diseases are not encouraging.🧵”
COVID and brain fog.
For millions, it’s the most disabling legacy of the pandemic.
Now, a new brain imaging study reveals a clear biological basis - and the parallels with other diseases are not encouraging.🧵
Molecular Imaging Findings on Acute and Long-Term Effects of COVID-19 on the Brain: A Systematic Review
“Molecular imaging techniques such as PET and SPECT have been used to shed light on how coronavirus disease 2019 (COVID-19) affects the human brain. We provide a systematic review that summarizes the current literature according to 5 predominant topics.”
Molecular imaging techniques such as PET and SPECT have been used to shed light on how coronavirus disease 2019 (COVID-19) affects the human brain. We provide a systematic review that summarizes the current literature according to 5 predominant topics.
Systemic increase of AMPA receptors associated with cognitive impairment of long COVID | Brain Communications | Oxford Academic
“Long COVID primarily presents with persistent cognitive impairment (Cog-LC), imposing a substantial and lasting global burden. Even after the pandemic, there remains a critical global need for diagnostic and therapeutic strategies targeting Cog-LC.”
Long COVID primarily presents with persistent cognitive impairment (Cog-LC), imposing a substantial and lasting global burden. Even after the pandemic, there remains a critical global need for diagnostic and therapeutic strategies targeting Cog-LC.